ABSTRACT:

Research Article

SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 1,2,4-TRIAZOLES.

R.U.ROY, A. R. DESAI AND K.R.DESAI.

Department of chemistry, Veer Narmad South Gujarat University, Surat-395007, India.

Several 3-(4'-nitrophenyl)-4-(4''-chloro benzamido)-5-substituted phenyl)-4H-1,2,4-triazole (3a-3e) and 3-(4'-nitrophenyl)-4-(4''-methyl benzenesulphonamido)-5-substituted phenyl)-4H-1,2,4-triazole (4a-4e) have been synthesised. Representative compounds were screened for antibacterial, antifungal activity. Most of them showed significant antibacterial activity.