ABSTRACT:
Research Article
Synthesis and Antibacterial activity of Chalcones and Pyrimidine-2-ones
A. K. PAREKH* and K. K. DESAI
Department of Chemistry,
Veer Narmad South Gujarat University,
Surat - 395 007. India.
Some new chalcones have been prepared by Claisen-schmidt condensation of ketone and different aromatic aldehydes. These chalcones on condensation with urea in presence of acid gave Pyrimidine-2-ones. The synthesized compounds have been characterized by elemental analysis, IR and 1H NMR spectral data. They have been screened for their antibacterial activity against Gram positive bacteria B. subtillis & S. aureus and Gram negative bacteria E. coli & S. typhi
